| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IP, IHC-P, ELISA | 79 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:100-500 IHC-P=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DVL2 Mouse Monoclonal Antibody detects endogenous levels of DVL2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DVL2 also known as Dishevelled 2, DVL-2 is a member of the dishevelled (dsh) protein family. DVL2 plays a crucial role in the Wnt signaling pathway, which is essential for various cellular processes, including cell proliferation, differentiation, and embryonic development. DVL2 is primarily located in the cytoplasm and translocates to the plasma membrane upon Wnt signaling activation, where DVL2 interacts with frizzled receptors. This localization facilitates the downstream signaling cascade that influences gene expression and cellular behavior. Dysregulation of DVL2 and associated pathways has been implicated in several diseases, including cancer and neurodegenerative disorders, making DVL2 a significant target for research. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431, MCF7, THP-1, K562 cells, using DVL2 Mouse Monoclonal Antibody (EAB22715) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 79 kDa; Observed band size: 90 kDa |
