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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 78 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DVL3 Rabbit Polyclonal Antibody detects endogenous levels of DVL3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DVL3(Dishevelled 3) is a member of the dishevelled protein family. DVL3 plays a crucial role in the Wnt signaling pathway, which regulates cell proliferation, differentiation, and embryonic development. Disruption of DVL3 function has been implicated in various developmental disorders and cancers, making DVL3 a significant target for research in understanding these diseases. DVL3 interacts with several key proteins, including frizzled receptors and axin, which are vital for proper functioning of the Wnt pathway. These interactions underscore DVL3′s importance in maintaining cellular homeostasis and potential as a therapeutic target in Wnt-related pathologies. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using DVL3 Rabbit Polyclonal Antibody (EAB11313) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human brain tissue, using DVL3 Rabbit Polyclonal Antibody (EAB11313) at 1:100 dilution.
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