RCAS1 Rabbit Polyclonal Antibody
Catalog #:EAB11323
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 24 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000
Product Information
Conjugate Unconjugate
Specificity RCAS1 Rabbit Polyclonal Antibody detects endogenous levels of RCAS1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

O00559

Entrez Gene ID

9166

Product Description

RCAS1 also known as EBAG9 is an estrogen-regulated protein that plays a critical role in immune evasion of tumor cells. RCAS1 is primarily located on the cell membrane and in soluble forms, where RCAS1 interacts with a putative receptor on peripheral lymphocytes, thereby inhibiting T lymphocyte growth and promoting apoptosis. RCAS1 presence in various cancers, including uterine, ovarian, and lung cancers, highlights RCAS1 significance in tumor progression and immune escape mechanisms. High levels of RCAS1 expression are associated with advanced tumor stages and poor prognoses in cancer patients, making RCAS1 a potential biomarker for assessing tumor aggressiveness.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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