TCF1/TCF7 Rabbit Polyclonal Antibody
Catalog #:EAB11337
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 42 Human, Mouse
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity TCF1/TCF7 Rabbit Polyclonal Antibody detects endogenous levels of TCF1/TCF7 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P36402

Entrez Gene ID

6932

Product Description

TCF1 also known as TCF7 is a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. TCF1 plays a crucial role in lymphoid cell development as a DNA-binding transcriptional activator. TCF1 is activated through the Wnt signaling pathway, which is essential for regulating gene expression during cell differentiation and proliferation. TCF1 contains a high mobility group (HMG) box that facilitates binding to DNA, allowing regulation of Wnt target genes. TCF1 exists in several splice variants, including TCF1A, which share a conserved amino terminus but differ in carboxy terminal sequences, potentially influencing functional roles in various cellular contexts. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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