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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 21 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MIST1 Rabbit Polyclonal Antibody detects endogenous levels of MIST1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MIST1 also known as BHLHB8, BHLHA15 is a secretory cell transcription factor that belongs to the basic helix-loop-helix superfamily. MIST1 features a basic helix-loop-helix (bHLH) domain, which is crucial for its role as a transcription factor. The bHLH domain allows MIST1 to bind to E-box motifs in the promoter or enhancer regions of various developmentally regulated genes, functioning as either a transcriptional activator or repressor. MIST1 interacts with E-proteins such as E12 and E47, and plays a significant role in regulating the transcriptional activity of MyoD, a key protein in muscle cell development. By acting as a repressor of MyoD activity, MIST1 ensures that myoblast populations remain undifferentiated, which is vital for muscle development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse Pancreas cells, using MIST1 Rabbit Polyclonal Antibody (EAB11359) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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