| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 41 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Bif-1 Rabbit Polyclonal Antibody detects endogenous levels of Bif-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Bif-1 also known as Endophilin B1, SH3GLB1 is a member of the endophilin family, which plays a crucial role in maintaining mitochondrial morphology and regulating the dynamics of the outer mitochondrial membrane, which is essential for cellular energy production and apoptosis regulation. The N-terminal domain of Bif-1 exhibits significant similarity to the lipid-binding and -modifying domain of class A Endophilins, highlighting involvement in lipid metabolism and membrane dynamics. Additionally, Bif-1′s interaction with other proteins, such as Amphiphysin and Dynamin, underscores importance in presynaptic vesicle trafficking at nerve terminals, a process vital for neurotransmitter release and synaptic plasticity. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using Bif-1 Rabbit Polyclonal Antibody (EAB11361) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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