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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 117 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TIF1α/TRIM24 Rabbit Polyclonal Antibody detects endogenous levels of TIF1α/TRIM24 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TIF1α also known as TRIM24 is a member of the tripartite motif (TRIM) family. TIF1α plays a crucial role in mediating transcriptional regulation by interacting with the activation function 2 (AF2) region of several nuclear receptors, such as estrogen, retinoic acid, and vitamin D3 receptors, which are essential for various physiological processes including development, metabolism, and cellular differentiation. TIF1α is localized to nuclear bodies and associates with chromatin and heterochromatin-associated factors, highlighting its importance in gene expression regulation. As a member of the tripartite motif (TRIM) family, TIF1α contains three zinc-binding domains (RING, B-box type 1, and B-box type 2) along with a coiled-coil region, which are critical for structural integrity and functional interactions. |
| Product Image Gallery | |
 Western blot analysis of extracts on COLO205, HepG2, NIH/3T3 cells, using TIF1α/TRIM24 Rabbit Polyclonal Antibody (EAB11391) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human breast cancer tissue, using TIF1α/TRIM24 Rabbit Polyclonal Antibody (EAB11391) at 1:100 dilution.
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