| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 47 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AGK Rabbit Polyclonal Antibody detects endogenous levels of AGK protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AGK also known as MULK is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism, AGK plays a crucial role in lipid metabolism. AGK functions as a lipid kinase that phosphorylates monoacylglycerol and diacylglycerol, leading to the production of lysophosphatidic acid (LPA) and phosphatidic acid (PA). The generation of LPA is significant as LPA is involved in various signaling pathways, including the transactivation of the epidermal growth factor receptor (EGFR) and extracellular signal-regulated kinase (ERK), which promote cell growth and proliferation. Notably, AGK overexpression has been linked to the initiation and progression of prostate cancer, highlighting AGK′s potential as a therapeutic target. |
| Product Image Gallery | |
 Western blot analysis of extracts on SH-SY5Y cells, using AGK Rabbit Polyclonal Antibody (EAB11398) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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