| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB | 69 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BMAL1 Rabbit Monoclonal Antibody detects endogenous levels of BMAL1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BMAL1 is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. BMAL1 plays a crucial role in circadian rhythm regulation by forming a heterodimer with Clock protein, which then binds to promoter regions of target genes such as mPer1. This interaction maintains the body′s internal clock, influencing physiological processes including sleep-wake cycles, hormone release, and metabolism. Disruptions in BMAL1 function can lead to circadian rhythm disorders and have been linked to metabolic syndromes and other health issues. Additionally, BMAL1 belongs to a larger family of transcription factors including aromatic hydrocarbon receptor (AhR) and nuclear translocator proteins (Arnt 1 and Arnt 2), which are essential for ligand-dependent activation of genes involved in detoxification processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on TF1, SKOV3, Mouse lung, Rat liver cells, using BMAL1 Rabbit Monoclonal Antibody (EAB22464) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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