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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, FC, ELISA | 67 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IF/ICC=1:100-500 FC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TORC1/CRTC1 Mouse MonoclonalAntibody detects endogenous levels of TORC1/CRTC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CRTC1 (CREB-Regulated Transcription Coactivator 1) also known as MECT1, TORC1 or KIAA0616 is a protein that in humans is encoded by the CRTC1 gene. The TORC (transducer of regulated cAMP response element-binding) proteins, TORC1 and TORC2, are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner. The translocation of TORC proteins is a conserved step in the activation of CRE-mediated gene expression induced by cAMP. TORC1 and TORC2 operate via phosphorylation-dependent interactions. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293 cells, using TORC1/CRTC1 Mouse MonoclonalAntibody (EAB21175) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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