| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 32 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Olig2 Rabbit Polyclonal Antibody detects endogenous levels of Olig2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Olig2 also known as BHLHB1 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. Olig2 plays a crucial role in the development of oligodendrocytes, which are essential for the formation of myelin sheaths that insulate nerve fibers in the central nervous system. This myelination is vital for proper neuronal function and signal transmission, and disruptions in OLIG2 expression can lead to various neurological disorders. OLIG2 is predominantly expressed in the embryonic brain and is involved in regulating oligodendrogenesis, making OLIG2 a key player in the development of the nervous system. Additionally, OLIG2 interacts with the Nkx-2.2 homeodomain protein, which is critical for ventral neuronal patterning during embryonic development. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7, Mouse barin cells, using Olig2 Rabbit Polyclonal Antibody (EAB12021) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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