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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB | 49 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-MAZ (Thr72) Rabbit Polyclonal Antibody detects endogenous levels of MAZ protein only when phosphorylated at Thr72. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MAZ also known as ZF87, Pur-1 is a crucial transcription factor that plays a significant role in regulating gene expression by participating in both initiation and termination of transcription. MAZ functions as a transcriptional repressor, exerting effects independently of the c-Myc promoter, which is essential for maintaining proper cellular function and preventing aberrant gene expression. MAZ protein is primarily located in the nucleus, where MAZ interacts with various transcription factors, including SP1, to modulate the expression of genes such as the parathyroid hormone receptor and serotonin 1A receptor. This interaction is vital for tissue-specific gene expression, as competition between MAZ and SP1 can influence the regulation of the PNMT gene, highlighting MAZ′s importance in cellular differentiation and development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse lung cells, using Phospho-MAZ (Thr72) Rabbit Polyclonal Antibody (EAB14759) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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