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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IF/ICC | 39 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IF/ICC=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | SLP-2 Rabbit Monoclonal Antibody detects endogenous levels of SLP-2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SLP-2 also known as STOML2, EPB72-like 2 is a 356 amino acid protein that belongs to the mec-2 family and is expressed at low levels across various tissues, with particularly high expression in heart, liver, and pancreas. SLP-2 is primarily localized in the cytoplasm, with some presence on the membrane, which is crucial for regulating ion channel conductances and organizing lipid rafts rich in sphingolipids and cholesterol. These lipid rafts are essential for various cellular processes, including signal transduction and membrane trafficking, highlighting SLP-2′s importance in maintaining cellular homeostasis and potentially influencing tumorigenesis, as SLP-2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth associated with varying levels of SLP-2 suggest involvement in endometrial tumorigenesis, making SLP-2 a significant target for further research in cancer biology. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, Raw264.7 cells, using SLP-2 Rabbit Monoclonal Antibody (EAB22656) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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