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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, FC, ELISA | 134 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 FC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Jagged1 Mouse Monoclonal Antibody detects endogenous levels of Jagged1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Jagged1 also known as JAG1, CD339 is a type I membrane-anchored multidomain protein and a ligand of the Notch receptor. Jagged1 plays a crucial role in the Notch signaling pathway, which is essential for various developmental processes, including cell fate determination and tissue differentiation. Specifically, Jagged1 acts as a ligand for Notch receptors, facilitating communication between adjacent cells and influencing developmental pathways. This interaction is particularly important in cardiovascular development and hematopoiesis, where Jagged1 helps regulate the balance between cell proliferation and differentiation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using Jagged1 Mouse Monoclonal Antibody (EAB22249) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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