www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB | 92 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-FGFR2 (Ser782) Rabbit Polyclonal Antibody detects endogenous levels of FGFR2 only when phosphorylated at Ser782. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FGFR also known as CD332, Bek is a member of the fibroblast growth factor receptor family. Located on the cell surface, FGFR2 binds to FGF ligands, initiating a cascade of intracellular signaling events that are essential for tissue development, repair, and maintenance. The structure of FGFR2 includes an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular tyrosine kinase domain, which are pivotal for its role in signal transduction and interaction with downstream signaling molecules like FRS2 and PLCγ. FGFR2 undergoes post-translational modifications, including glycosylation, which are crucial for its proper folding, stability, and functional activation, thereby enhancing its ability to interact with specific intracellular partners. |
