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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB | 88 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FGFR3 Rabbit Monoclonal Antibody detects endogenous levels of FGFR3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FGFR3 also known as CD333, ACH a member of the fibroblast growth factor receptor (FGFR) family, plays a crucial role in regulating cell growth, differentiation, and tissue repair. FGFR-3 is primarily located on the cell surface, where FGFR-3 binds to fibroblast growth factors, initiating a cascade of intracellular signaling that influences cellular processes such as proliferation and survival. Proper functioning of FGFR-3 is vital for normal skeletal development, and mutations in FGFR-3 can lead to a range of skeletal dysplasias, including achondroplasia and thanatophoric dysplasia, highlighting FGFR-3′s importance in human health. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, A549, Mouse brain cells, using FGFR3 Rabbit Monoclonal Antibody (EAB22204) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 88 kDa; Observed band size: 95-135 kDa |
