DJ-1 Mouse Monoclonal Antibody
Catalog #:EAB22807
Host / Isotype Clonality Applications MW (kDa) Reactivity
Mouse IgG1 Monoclonal WB, IHC-P, FC, ELISA 20 Human
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:100-500 
FC=1:50-200
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity DJ-1 Mouse Monoclonal Antibody detects endogenous levels of DJ-1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q99497 

Entrez Gene ID

11315 

Product Description

DJ-1 also known as DJ1, PARP7 is a highly-conserved protein that plays a crucial role in cellular processes, particularly in protecting cells from oxidative stress and maintaining mitochondrial function. DJ-1′s ability to regulate the androgen receptor by forming a complex with PIASxα highlights DJ-1′s importance in hormonal signaling pathways, which can have significant implications in both cancer biology and neurodegenerative diseases. The gene encoding DJ-1 is located on chromosome 1p36.23, a region associated with various chromosomal abnormalities in tumor cells, and mutations in this gene have been linked to Parkinson′s disease, underscoring DJ-1′s relevance in neuroprotection. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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