GluA2/GluR-2 Mouse Monoclonal Antibody
Catalog #:EAB22083
Host / Isotype Clonality Applications MW (kDa) Reactivity
Mouse IgG1 Monoclonal WB, FC, ELISA 99 Human
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
FC=1:50-200
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity GluA2/GluR-2 Mouse Monoclonal Antibody detects endogenous levels of GluA2/GluR-2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P42262

Entrez Gene ID

2891

Product Description

GluR-2 also known as GRIA2 is a critical component of the AMPA receptor complex, which mediates fast excitatory neurotransmission in the central nervous system. GluR-2 is primarily located in the postsynaptic membrane of neurons, where GluR-2 plays a vital role in synaptic plasticity, a fundamental mechanism underlying learning and memory. Proper functioning of GluR-2 is essential for maintaining synaptic strength and facilitating communication between neurons. Alterations in GluR-2 expression or function have been implicated in various neurological disorders, including epilepsy, schizophrenia, and neurodegenerative diseases, highlighting GluR-2′s significance in both normal brain function and disease pathology. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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