www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 87 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FAP Rabbit Monoclonal Antibody detects endogenous levels of FAP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. FAP is essential for remodeling developing tissues, highlighting FAP′s importance in both normal and pathological processes. Structurally, FAP is an integral membrane gelatinase composed of N-glycosylated, proteolytically inactive subunits, which underscores unique functional properties. FAP expression on chondrocyte membranes is upregulated by cytokines interleukin-1 and oncostatin M, and increases in patients with osteoarthritis. This expression is co-localized with matrix metalloproteinases MMP-1 and MMP-13, as well as CD44 variants v3 and v7/8, indicating involvement in complex cellular interactions. |
| Product Image Gallery | |
 Western blot analysis of extracts on U87MG, Mouse skin cells, using FAP Rabbit Monoclonal Antibody (EAB22336) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
