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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 38 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACOX1 Mouse Monoclonal Antibody detects endogenous levels of ACOX1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACOX1(Acyl-coenzyme A oxidase 1) is a crucial 660 amino acid protein localized in the peroxisome, where ACOX1 plays a vital role in lipid metabolism. Specifically, ACOX1 catalyzes the desaturation of very long chain acyl-CoA substrates into 2-trans-enoyl-CoA, a reaction that is essential for the breakdown of fatty acids and involves the use of FAD as a cofactor. This enzymatic activity not only facilitates energy production but also contributes to the regulation of cellular lipid levels, which is critical for maintaining cellular homeostasis. Defects in ACOX1 can lead to pseudoneonatal adrenoleukodystrophy (pseudo-NALD), a serious condition characterized by neurological impairments and metabolic dysfunctions, underscoring ACOX1′s significance in human health. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2, Mouse liver cells, using ACOX1 Mouse Monoclonal Antibody (EAB22833) at 1:3000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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