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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 69 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | eIF4B Rabbit Monoclonal Antibody detects endogenous levels of eIF4B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
eIF4B (Eukaryotic translation initiation factor 4B) is a crucial 611 amino acid protein that plays a significant role in the regulation of protein synthesis by facilitating the binding of mRNA to ribosomes, a process essential for the translation of genetic information into functional proteins. Specifically, eIF4B is involved in the assembly of the translation initiation complex by facilitating the binding of mRNA to the ribosome, which is essential for accurate and efficient protein synthesis. eIF4B contains a single RNA recognition motif and interacts with other initiation factors, such as eIF4A, enhancing their activity and promoting the unwinding of mRNA structures that can inhibit translation. The gene encoding eIF4B is located on human chromosome 12, a region rich in genes and significant in various cellular processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549 cells, using eIF4B Rabbit Monoclonal Antibody (EAB22932) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 69 kDa; Observed band size: 80 kDa |
