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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 79 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TAB3 Rabbit Polyclonal Antibody detects endogenous levels of TAB3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TAB3 plays a crucial role in activating NF-kB and AP-1 transcription factors, which are essential for regulating immune responses and inflammation. When TAB3 is overexpressed, TAB3 can enhance signaling pathways that lead to gene transcription involved in these processes, influencing cellular responses to proinflammatory cytokines such as TNF-α and IL-1. TAB3 interacts with TAK1, forming complexes that are pivotal for mediating effects of various stimuli, including stress and inflammatory signals. This interaction is vital for proper immune system function and cellular homeostasis, making TAB3 an important target for research in inflammation and immune-related diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on LOVO, Mouse slpeen cells, using TAB3 Rabbit Polyclonal Antibody (EAB13854) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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