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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | IHC-P, IF, ELISA | 28 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Oncostatin M/OSM Rabbit Polyclonal Antibody detects endogenous levels of Oncostatin M/OSM protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
OSM(Oncostatin M) is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. OSM plays a crucial role in regulating cell growth and differentiation, particularly in inflammation and cancer. OSM was initially isolated from the conditioned medium of U937 human histiocytic leukemia cells that had been induced to differentiate into macrophage-like cells. OSM inhibits the growth of a wide range of human tumor cell lines while sparing normal human fibroblasts, highlighting OSM′s potential as a therapeutic target in oncology. OSM interacts with high-affinity binding sites on both normal and tumor cells, and OSM expression is significantly elevated in activated monocytic and lymphocytic cell lines, as well as in normal adherent macrophages. |
| Product Image Gallery | |
 Immunohistochemistry of paraffin-embedded Human brain tissue, using Oncostatin M/OSM Rabbit Polyclonal Antibody (EAB12114) at 1:200 dilution.
 Immunohistochemistry of paraffin-embedded Human colon tissue, using Oncostatin M/OSM Rabbit Polyclonal Antibody (EAB12114) at 1:200 dilution.
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