VASH1 Rabbit Polyclonal Antibody
Catalog #:EAB11884
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, ELISA 41 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity VASH1 Rabbit Polyclonal Antibody detects endogenous levels of VASH1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q7L8A9

Entrez Gene ID

22846

Product Description

VASH1(Vasohibin 1)  also known as TTCP1 plays a crucial role in regulating angiogenesis, which is essential for normal physiological processes such as wound healing and tissue repair, as well as in pathological conditions like cancer. This secreted protein is primarily expressed in endothelial cells, particularly in brain and placental tissues, where VASH1 is involved in a self-regulating feedback mechanism that inhibits angiogenesis in an autocrine manner. By inhibiting endothelial cell proliferation, migration, and network formation, VASH1 serves as a critical endogenous inhibitor that balances effects of pro-angiogenic factors like vascular endothelial growth factor (VEGF) and fibroblast growth factor 2. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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