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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 160 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-DAPK1 (Ser289) Rabbit Polyclonal Antibody detects endogenous levels of DAPK1 only when phosphorylated at Ser289. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DAPK1(Death associated protein kinase 1) also known as DAPK is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 plays a crucial role in the regulation of apoptosis, a vital process for maintaining cellular homeostasis and preventing tumorigenesis. DAPK1 is characterized by its "death domain," which is essential for mediating apoptosis in response to various stimuli, including interferon-gamma. Introduction of DAPK1 into highly metastatic carcinoma clones lacking DAPK1 expression has been shown to suppress metastasis, highlighting DAPK1′s significant role in cancer biology. DAPK1 interacts with other proteins involved in apoptotic signaling pathways, underscoring DAPK1′s importance in cellular responses to stress and damage. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells treated with LPS, using Phospho-DAPK1 (Ser289) Rabbit Polyclonal Antibody (EAB14861) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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