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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 49 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cytokeratin 20 Mouse Monoclonal Antibody detects endogenous levels of Cytokeratin 20 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cytokeratin 20 also known as CK-20, Keratin 20, KRT20 is a member of the keratin family. Cytokeratin 20 is primarily located in the cytoplasm of epithelial cells, particularly in the gastrointestinal tract, where Cytokeratin 20 is abundantly expressed in goblet cells and enterocytes. Such localization plays a significant role in maintaining the structural integrity and function of epithelial tissues, which are essential for barrier formation and nutrient absorption. Cytokeratin 20 serves as a valuable marker for pancreatic and colorectal cancers, aiding in the differentiation of various carcinomas, including distinguishing renal oncocytomas from renal cell carcinomas. |
| Product Image Gallery | |
 Western blot analysis of extracts on SW480 cells, using Cytokeratin 20 Mouse Monoclonal Antibody (EAB21317) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue, using Cytokeratin 20 Mouse Monoclonal Antibody (EAB21317) at 1:200 dilution.
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