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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 59 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 IF=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TREK-2 Rabbit Polyclonal Antibody detects endogenous levels of TREK-2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TREK-2 also known as KCNK10 is a member of the tandem-pore potassium channel family. TREK-2 plays a crucial role in maintaining the resting membrane potential and regulating cellular excitability. TREK-2 contributes to neuronal signaling and the modulation of synaptic transmission. TREK-2 is primarily localized in the cerebellum, spleen, and testis, and TREK-2′s expression in these tissues underscores its significance in various physiological processes, including sensory transduction and the response to mechanical stimuli. TREK-2 consists of 538 amino acids and features two pore-forming domains and four transmembrane segments, which are essential for its function as a potassium channel. TREK-2 exhibits inward rectification and is activated by arachidonic acid and other unsaturated fatty acids, highlighting TREK-2′s role in cellular responses to metabolic changes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, Mouse brain, Rat brain cells, using TREK-2 Rabbit Polyclonal Antibody (EAB12127) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using TREK-2 Rabbit Polyclonal Antibody (EAB12127) at 1:200 dilution.
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