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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 47 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PAX6 Rabbit Polyclonal Antibody detects endogenous levels of PAX6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PAX6(Paired box 6) is a crucial transcriptional regulator that plays a significant role in eye development and is essential for the formation of various ocular structures.. PAX6 function is vital, as mutations in the PAX6 gene can lead to severe congenital eye disorders, such as aniridia, characterized by the absence of the iris, which can result in significant vision impairment or blindness. PAX6 is involved in other anterior segment malformations, including Peters anomaly, which is marked by corneal clouding and various adhesions affecting the eye′s structures. Pax-6 gene encodes a transcriptional regulator that binds to specific DNA sequences through its paired-type DNA-binding domain, which consists of two subdomains that work together to regulate gene expression critical for eye development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549 cells, using PAX6 Rabbit Polyclonal Antibody (EAB12152) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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