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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 37 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LSP1 Rabbit Polyclonal Antibody detects endogenous levels of LSP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LSP1 also known as pp52 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific phosphoprotein, playing a crucial role in the immune response by regulating leukocyte functions such as motility and chemotaxis. LSP1 is involved in cytoskeletal remodeling, which is essential for the movement and activation of immune cells, including B and T lymphocytes, granulocytes, and macrophages. The gene encoding LSP1 is located on human chromosome 11p15.5, a region associated with tumor-related chromosomal translocations in chronic lymphocytic leukemia, highlighting LSP1′s potential significance in cancer biology. The promoter of LSP1 contains critical elements that regulate transcriptional activity, including Ets and SP1 motifs, which are vital for precise expression in response to various signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using LSP1 Rabbit Polyclonal Antibody (EAB14869) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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