www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 50 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Sox10 Rabbit Polyclonal Antibody detects endogenous levels of Sox10 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Sox10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox10 plays a crucial role in glial cell development and is essential for proper myelin formation in the nervous system, which enables efficient nerve signal transmission. Mutations in Sox10 can lead to severe developmental disorders, including Waardenburg syndrome and other neurocristopathies, highlighting Sox10′s importance in both normal physiology and disease. The Sox gene family, including Sox10, is characterized by the HMG-box domain, which facilitates sequence-specific DNA binding, thereby influencing gene expression and cell fate decisions during embryonic development. |
| Product Image Gallery | |
 Western blot analysis of extracts on A375, Rat lung cells, using Sox10 Rabbit Polyclonal Antibody (EAB14674) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 50 kDa; Observed band size: 60 kDa |
