| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 45 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rapsyn Rabbit Polyclonal Antibody detects endogenous levels of Rapsyn protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rapsyn also known as RAPSN is a member of a family of proteins that are receptor associated proteins of the synapse. Rapsyn plays a crucial role in neuromuscular transmission. Rapsyn, or receptor-associated protein of the synapse, is primarily expressed in the postsynaptic membrane of skeletal muscle, where rapsyn is essential for the clustering of nicotinic acetylcholine receptors (nAChR). Rapsyn′s ability to self-associate through tetra-tricopeptide repeats facilitates interaction with the large intracellular domain of the nAChR α subunit, which is vital for proper localization and function of these receptors at the neuromuscular junction. Rapsyn not only modifies AChR trafficking within the cell but is also critical for agrin-induced AChR clustering, a process essential for functional synapse formation. |
| Product Image Gallery | |
 Western blot analysis of extracts on U2OS cells, using Rapsyn Rabbit Polyclonal Antibody (EAB14524) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue, using Rapsyn Rabbit Polyclonal Antibody (EAB14524) at 1:200 dilution.
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