| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, ELISA | 27 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | VEGF-A Mouse Monoclonal Antibody detects endogenous levels of VEGF-A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
VEGF-A also known as VPF, VEGF is a member of the PDGF/VEGF growth factor family. VEGF-A plays a crucial role in angiogenesis, the process of new blood vessel formation, which is vital for supplying nutrients and oxygen to tissues, particularly during development and in response to injury. VEGF-A dysregulation is implicated in various pathological conditions, including cancer, where VEGF-A promotes tumor growth and metastasis by enhancing blood supply to the tumor microenvironment. VEGF-A exists as a dimeric glycoprotein and exhibits structural similarities to platelet-derived growth factor (PDGF), with multiple isoforms generated through alternative mRNA splicing. VEGF-A expression is tightly regulated, and VEGF-A mRNA is often found in primary tumors, indicating VEGF′s potential as a therapeutic target. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HEK293, HuvEc cells, using VEGF-A Mouse Monoclonal Antibody (EAB10291) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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