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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 54 | Human, Mouse, Rat, Pig |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:2000-10000 IHC-P=1:200-1000 IF/ICC=1:200-1000 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MMP-3 Mouse Monoclonal Antibody detects endogenous levels of MMP-3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MMP-3(Matrix metallopeptidase 3) also known as Stromelysin-2 is a member of the matrix metalloproteinase family, which plays a crucial role in the remodeling of the extracellular matrix by degrading various components, including collagen and proteoglycans, which is vital for processes such as tissue repair and development. MMP-3 is particularly important as MMP-3 not only activates procollagenase but also participates in the processing of other MMPs, thereby influencing various physiological and pathological processes, including wound healing, inflammation, and cancer progression. MMP-3 activation is tightly regulated and can occur through two distinct pathways: a slower direct activation by MMP-3 itself and a more rapid activation in conjunction with tissue or plasma proteinases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, PC12, Mouse brain, Rat brain cells, using MMP-3 Mouse Monoclonal Antibody (EAB21403) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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