| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 84 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-RSK2 (Ser227) Rabbit Polyclonal Antibody detects endogenous levels of RSK2 only when phosphorylated at Ser227. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RSK2 also known as p90RSK2, RPS6KA3 a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK2 plays a crucial role in cellular signaling pathways, particularly in response to growth factors and mitogens. RSK2 is primarily located in the cytoplasm, where activation by phosphorylation occurs in response to extracellular signals, leading to regulation of various cellular processes such as cell growth, proliferation, and survival. RSK2′s cytoplasmic localization enables rapid response to signaling cascades initiated by receptor tyrosine kinases, thereby influencing downstream targets essential for cellular function and adaptation. RSK2 interacts with several key proteins, including extracellular signal-regulated kinases (ERKs), which are vital for mediating effects of growth factors and stress signals. |
| Product Image Gallery | |
 Western blot analysis of extracts on PC12 cells, using Phospho-RSK2 (Ser227) Rabbit Polyclonal Antibody (EAB14870) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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