Phospho-ILK1 (Ser246) Rabbit Polyclonal Antibody
Catalog #:EAB12137
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal IHC-P, IF, ELISA 51 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
IHC-P=1:50-300 
IF=1:50-300
Product Information
Conjugate Unconjugate
Specificity Phospho-ILK1 (Ser246) Rabbit Polyclonal Antibody detects endogenous levels of ILK1 protein only when phosphorylated at Ser246.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q13418

Entrez Gene ID

3611

Product Description

ILK1 also known as P59, ILK is a protein with a kinase-like domain and four ankyrin-like repeats. ILK1 plays a crucial role in cellular signaling and is primarily located at the cell membrane, where ILK1 interacts with integrins, which are essential for cell adhesion and communication with the extracellular matrix. This localization enables ILK1 to mediate the transduction of signals that influence various biological processes, including cell growth, differentiation, and migration. ILK1 interaction with integrins facilitates the assembly of the cytoskeleton and promotes cellular responses to external stimuli, thereby impacting tissue development and repair. ILK1 has been implicated in tumorigenesis, as expression levels can influence the behavior of cancer cells, making ILK1 a significant target for research in cancer biology. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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