Protein Inhibitors - Cyclic Pifithrin-α hydrobromide (CAS: 511296-88-1)

Cyclic Pifithrin-α hydrobromide (CAS: 511296-88-1)

Catalog #：EBC51081

Cyclic Pifithrin-α hydrobromide
(CAS: 511296-88-1)

If you want to get a larger packsize, Please contact your local distributor or
email us atinfo@ebiocell.com

Please Select The Country You Are In To Find Your Local Distributor.

Product Information

Synonym(s)

pifithrin-α. p53 inhibitor, pifithrin-alpha analog

Chemical Name

2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole

Application

Cyclic Pifithrin-α hydrobromide is a cyclic analog of pifithrin-α

CAS Number

511296-88-1

Purity

≥99.5%

Molecular Weight

349.29

Molecular Formula

C₁₆H₁₇BrN₂S

SMILES

CC1=CC=C(C=C1)C2=CN3C4=C(CCCC4)SC3=N2.Br

Target & IC50

Mus musculus: EC5050 = 2.5 μM

Solubility

DMSO: 27 mg/mL (77.30 mM)
Ethanol: 3 mg/mL (8.59 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Cyclic Pifithrin-alpha is a reversible and cell-permeable inhibitor of p53, which plays a crucial role in apoptosis, angiogenesis, and genomic stability. The cyclic form is the more stable and less cytotoxic version of the molecule. It is reported to be capable of increasing the efficiency of inducing pluripotent stem cells.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol