Protein Inhibitors - Stat3 Inhibitor VI, S3I-201 (CAS: 501919-59-1)

Stat3 Inhibitor VI, S3I-201 (CAS: 501919-59-1)

Catalog #：EBC51123

Stat3 Inhibitor VI, S3I-201
(CAS: 501919-59-1)

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Product Information

Synonym(s)

NSC 74859, NSC-74859, S3I201

Chemical Name

2-Hydroxy-4-[[2-(4-methylphenyl)sulfonyloxyacetyl]amino]benzoic acid

Application

Stat3 Inhibitor VI, S3I-201 is an inhibitor of Stat3 phosphorylation and dimerization

CAS Number

501919-59-1

Purity

≥99.0%

Molecular Weight

365.36

Molecular Formula

C₁₆H₁₅NO₇S

SMILES

CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O

Target & IC50

Stat3: IC50 = 86 μM

Solubility

DMSO: 36.5 mg/mL (100 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
S31-201 is benezoic acid based small molecule, which inhibits the Stat3 transcription factor by blocking the phosphorylation and dimerization events necessary For activation. Many cancers express aberrant behavior in the Stat3 growth factor, making this compound a valuable tool For perturbing the chemistry of such systems.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol