Monoclonal Antibodies - GSK-3β Mouse Monoclonal Antibody

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GSK-3β Mouse Monoclonal Antibody

Catalog #：EAB10227

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10227-30UL	In Stock	30ul	€115.70
EAB10227-100UL	In Stock	100ul	€258.70
EAB10227-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P, IF
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	47
Conjugate	Unconjugate
Specificity	GSK-3β Mouse Monoclonal Antibody detects endogenous levels of GSK-3β protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Glycogen synthase kinase 3 beta; GSK3β; GSK3beta; GSK3B
Gene Aliases	GSK3B
UniProt ID	P49841
Entrez Gene ID	2932

Product Description

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase that plays a crucial role in numerous signaling pathways, particularly those involved in glycogen metabolism and cellular adhesion, and has been linked to the pathogenesis of Alzheimer′s disease. GSK-3 exists in two isoforms, GSK-3α and GSK-3β, which differ in subcellular localization, with GSK-3α primarily found in the cytoplasm and GSK-3β localized in both the cytoplasm and nucleus. This differential localization is significant as GSK-3 may influence specific signaling pathways that each isoform regulates, thereby affecting cellular responses to various stimuli.

Product Image Gallery

Western blot analysis of extracts on Hela, Rat brain, NIH/3T3 cells, using GSK-3β Mouse Monoclonal Antibody (EAB10227) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Immunohistochemical analysis of paraffin-embedded Human stomach carcinoma tissue, using GSK-3β Mouse Monoclonal Antibody (EAB10227) at 1:200 dilution.

Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue, using GSK-3β Mouse Monoclonal Antibody (EAB10227) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol