United Kingdom| SKU-Pack Size | Availability | Size | Price | |
| EAB13136-30UL | In Stock | 30ul | £97.90 | |
| EAB13136-100UL | In Stock | 100ul | £218.90 | |
| EAB13136-200UL | In Stock | 200ul | £372.90 |
| Please select the country you are in to find your local distributor. |
| CUlabSciences | Phone:+44 (0) 1232 330008 | |
| Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
| United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC, ELISA |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| MW (kDa) | 53 |
| Conjugate | Unconjugate |
| Specificity | IkBε Rabbit Polyclonal Antibody detects endogenous levels of IkBε protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | NFKB inhibitor epsilon; IkappaB epsilon; IKBE; NFKBIE |
| Gene Aliases | NFKBIE |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IkBε plays a crucial role in the regulation of the NF-kB signaling pathway, which is essential for controlling immune responses, cell proliferation, and survival. IkBε is primarily located in the cytoplasm, where IkBε binds to NF-kB dimers, preventing their translocation to the nucleus and thereby inhibiting the expression of target genes involved in inflammation and immune responses. Proper functioning of IkBε is vital, as dysregulation can lead to various diseases, including cancer and autoimmune disorders. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Hela cells, using IkBε Rabbit Polyclonal Antibody (EAB13136) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 53 kDa; Observed band size: 45 kDa |
| Specific Protocols | |