Polyclonal Antibodies - Phospho-IkBε (Ser22) Rabbit Polyclonal Antibody

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Phospho-IkBε (Ser22) Rabbit Polyclonal Antibody

Catalog #：EAB13137

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB13137-30UL	In Stock	30ul	$163.50
EAB13137-100UL	In Stock	100ul	$343.50
EAB13137-200UL	In Stock	200ul	$553.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	53
Conjugate	Unconjugate
Specificity	Phospho-IkBε (Ser22) Rabbit Polyclonal Antibody detects endogenous levels of IkBε protein only when phosphorylated at Ser22.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	NFKB inhibitor epsilon; IkappaB epsilon; IKBE; NFKBIE
Gene Aliases	NFKBIE
UniProt ID	O00221
Entrez Gene ID	4794

Product Description

IkBε plays a crucial role in the regulation of the NF-kB signaling pathway, which is essential for controlling immune responses, cell proliferation, and survival. IkBε is primarily located in the cytoplasm, where IkBε binds to NF-kB dimers, preventing their translocation to the nucleus and thereby inhibiting the expression of target genes involved in inflammation and immune responses. Proper functioning of IkBε is vital, as dysregulation can lead to various diseases, including cancer and autoimmune disorders.

Product Image Gallery
Western blot analysis of extracts on Jurkat cells treated with TNFalpha, using Phospho-IkBε (Ser22) Rabbit Polyclonal Antibody (EAB13137) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide. Predicted band size: 53 kDa; Observed band size: 38 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol