RhoB a member of the Rho family of small GTPases. RhoB plays a crucial role in regulating the actin cytoskeleton, which is essential for various cellular processes such as cell migration, adhesion, and division. Proper RhoB function is vital for maintaining cellular integrity and facilitating communication between cells, particularly in the context of cancer progression where altered RhoB activity can lead to increased invasiveness and metastasis. RhoB is known to interact with several key proteins, including Rho-associated protein kinase (ROCK) and various guanine nucleotide exchange factors (GEFs), which further underscores RhoB importance in signal transduction pathways.