P63104

14-3-3 zeta is a member of the 14-3-3 protein family, which plays a crucial role in cellular signaling and regulation, particularly in cancer biology, where 14-3-3 zeta protein is involved in processes such as apoptosis, mitogenic signaling, and cell-cycle checkpoints. 14-3-3 zeta protein is primarily located in the cytoplasm, where 14-3-3 zeta protein interacts with various target proteins to modulate their activity and stability. This cytoplasmic localization allows 14-3-3 zeta protein to act as a regulatory hub, coordinating multiple signaling pathways essential for maintaining cellular homeostasis and responding to stress signals. Through binding to phosphorylated serine and threonine residues on ligands, 14-3-3 zeta protein can influence protein interactions and functions, impacting critical cellular processes.