Q04917

14-3-3 eta is a member of the 14-3-3 protein family, which plays a crucial role in cellular signaling pathways, particularly in regulating apoptosis, mitogenic signaling, and cell-cycle checkpoints, making 14-3-3 eta protein significant in cancer biology. 14-3-3 eta protein is primarily located in the cytoplasm and nucleus, where 14-3-3 eta protein interacts with various target proteins to modulate their activity. 14-3-3 eta protein′s ability to sequester proteins in the cytoplasm or facilitate their nuclear import/export is vital for maintaining cellular homeostasis and responding to stress signals. 14-3-3 eta protein′s interaction with ligands, which often contain a specific 14-3-3 consensus binding motif, is essential for regulating numerous cellular processes.