Q9Y6A5

TACC3 also designated ERIC1 is a a member of the transforming acidic coiled-coil (TACC) protein family, plays a crucial role in cell cycle regulation and mitotic spindle assembly, which are essential processes for proper cell division and maintaining genomic stability. TACC3 is primarily localized to the centrosomes and microtubules, where TACC3 is involved in organizing the microtubule network during mitosis. This localization is vital as TACC3 ensures accurate chromosome segregation, preventing aneuploidy, which is often associated with cancer development. TACC3′s interaction with microtubules and centrosomes highlights TACC3′s importance in cellular architecture and function, making TACC3 a significant target for research in cancer biology and therapeutic interventions.