| SKU-Pack Size | Availability | Size | Price | |
| EAB10639-30UL | In Stock | 30ul | €141.70 | |
| EAB10639-100UL | In Stock | 100ul | €297.70 | |
| EAB10639-200UL | In Stock | 200ul | €479.70 |
| Please select the country you are in to find your local distributor. |
| Betaclonal | Phone£º+34 (0)91 471 6763 | |
| 29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
| Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
| Product Information | |
| Applications | WB, IHC-P, IF/ICC, ELISA |
| Species Reactivity | Human, Mouse, Rat, Monkey |
| Host / Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF/ICC=1:50-300¡¡ |
| MW (kDa) | 39 |
| Conjugate | Unconjugate |
| Specificity | Phospho-Aurora B (Thr232) Rabbit Polyclonal Antibody detects endogenous levels of Aurora B only when phosphorylated at Thr232. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
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| Product Bioinformatics | |
| Synonym(s) | Aurora kinase B; AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; ARK-2; STK-1; STK12; PPP1R48; aurkb-sv1; aurkb-sv2; AURKB |
| Gene Aliases | AURKB |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Aurora B also known as ARK-2, AURKB is a member of the aurora kinase subfamily of serine/threonine kinases. Aurora B plays a crucial role in regulating centrosome separation, bipolar spindle assembly, and chromosome segregation during mitosis, making Aurora B essential for proper cell division and genomic stability. Aurora B is predominantly localized in the nucleus, where Aurora B associates with distinct components of the mitotic machinery, such as the spindle poles and midbody, highlighting Aurora B′s importance in the orchestration of mitotic events. Notably, Aurora B protein levels peak during the S and G2/M phases of the cell cycle, indicating Aurora B′s active involvement in cell cycle progression, while Aurora B′s unique genetic locus suggests distinct functions compared to Aurora A. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on COS7 cells treated with Nocodazole, using Phospho-Aurora B (Thr232) Rabbit Polyclonal Antibody (EAB10639) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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| Specific Protocols | |