Monoclonal Antibodies - Survivin Mouse Monoclonal Antibody

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Survivin Mouse Monoclonal Antibody

Catalog #：EAB10811

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10811-30UL	In Stock	30ul	$133.50
EAB10811-100UL	In Stock	100ul	$298.50
EAB10811-200UL	In Stock	200ul	$508.50

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email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF
Species Reactivity	Human, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500　 IF=1:50-300
MW (kDa)	16
Conjugate	Unconjugate
Specificity	Survivin Mouse Monoclonal Antibody detects endogenous levels of Survivin protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Baculoviral IAP repeat containing 5; API4; EPR-1; BIRC5
Gene Aliases	BIRC5
UniProt ID	O15392
Entrez Gene ID	332

Product Description

Survivin also known as BIRC5 is a member of the inhibitor of apoptosis (IAP) gene family. Survivin plays a crucial role in regulating cell division and inhibiting apoptosis, making survivin a vital component in cancer biology, as survivin overexpression is often associated with tumor progression and resistance to chemotherapy. Survivin is primarily located in the cytoplasm and nucleus of dividing cells, where survivin associates with the mitotic spindle during cell division, ensuring proper chromosomal segregation. Survivin localization is significant because survivin not only contributes to the survival of cancer cells but also serves as a potential biomarker for cancer diagnosis and prognosis.

Product Image Gallery
Western blot analysis of extracts on Hela, 293, PC12 cells, using Survivin Mouse Monoclonal Antibody (EAB10811) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human colon caricnoma tissue, using Survivin Mouse Monoclonal Antibody (EAB10811) at 1:500 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol