Polyclonal Antibodies - Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody

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Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody

Catalog #：EAB10839

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10839-30UL	In Stock	30ul	$163.50
EAB10839-100UL	In Stock	100ul	$343.50
EAB10839-200UL	In Stock	200ul	$553.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	59
Conjugate	Unconjugate
Specificity	Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody detects endogenous levels of LYN only when phosphorylated at Tyr507.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	JTK8; SAIDV; p53Lyn; p56Lyn; LYN
Gene Aliases	LYN
UniProt ID	P07948
Entrez Gene ID	4067

Product Description

LYN also known as JTK8 is a member of the Src family of non-receptor tyrosine kinases. LYN play a crucial role in various cellular processes, including the regulation of immune responses and hematopoiesis. LYN is predominantly expressed in hematopoietic tissues, where LYN is essential for normal immunoglobulin production and the modulation of immune cell signaling. LYN′s activity is tightly regulated, and LYN is typically maintained in an inactive state, becoming activated during specific cellular events, such as mitosis or immune receptor engagement. This regulation is vital for preventing aberrant signaling that could lead to uncontrolled cell proliferation or autoimmune disorders.

Product Image Gallery
Western blot analysis of extracts on 293 cells, using Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody (EAB10839) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 59 kDa; Observed band size: 53, 56 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol