Polyclonal Antibodies - Phospho-PTPα (Tyr798) Rabbit Polyclonal Antibody

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Phospho-PTPα (Tyr798) Rabbit Polyclonal Antibody

Catalog #：EAB10911

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB10911-30UL	In Stock	30ul	€141.70
EAB10911-100UL	In Stock	100ul	€297.70
EAB10911-200UL	In Stock	200ul	€479.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat, Monkey
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	91
Conjugate	Unconjugate
Specificity	Phospho-PTPα (Tyr798) Rabbit Polyclonal Antibody detects endogenous levels of PTPα only when phosphorylated at Tyr798.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Protein tyrosine phosphatase receptor type A; LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha; PTPRA
Gene Aliases	PTPRA
UniProt ID	P18433
Entrez Gene ID	5786

Product Description

PTPα also known as RPTPα, PTPRA is a member of the protein tyrosine phosphatase (PTP) family. PTPα plays a crucial role in cellular signaling by dephosphorylating and activating Src family tyrosine kinases, which are essential for regulating integrin signaling, cell adhesion, and growth factor responsiveness. PTPα is located in the cell membrane, where PTPα contains an extracellular domain, a single transmembrane segment, and two tandem intracytoplasmic catalytic domains, allowing PTPα to form constitutive dimers that enhance functional capacity. Additionally, PTPα serves as a receptor for the Helicobacter pylori vacuolating cytotoxin, VacA, highlighting PTPα′s importance in both normal cellular functions and pathogenic processes.

Product Image Gallery
Western blot analysis of extracts on Hela cells treated with Serum, using Phospho-PTPα (Tyr798) Rabbit Polyclonal Antibody (EAB10911) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide. Predicted band size: 91 kDa; Observed band size: 145 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol