Polyclonal Antibodies - DNA Ligase I/LIG1 Rabbit Polyclonal Antibody

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DNA Ligase I/LIG1 Rabbit Polyclonal Antibody

Catalog #：EAB14640

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14640-30UL	In Stock	30ul	￡97.90
EAB14640-100UL	In Stock	100ul	￡218.90
EAB14640-200UL	In Stock	200ul	￡372.90

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email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P, IF, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF=1:50-300
MW (kDa)	102
Conjugate	Unconjugate
Specificity	DNA Ligase I/LIG1 Rabbit Polyclonal Antibody detects endogenous levels of DNA Ligase I/LIG1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	LIG1; DNA ligase 1; DNA ligase I; ligase 1; ligase I; ATP-dependent; Lig-1; LIGI; Lig-I; DNLI1
Gene Aliases	LIG1
UniProt ID	P18858
Entrez Gene ID	3978

Product Description

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Product Image Gallery
Western blot analysis of extracts on HT29 cells, using DNA Ligase I/LIG1 Rabbit Polyclonal Antibody (EAB14640) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Predicted band size: 102 kDa; Observed band size: 133 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol