Monoclonal Antibodies - ABCB5 Mouse Monoclonal Antibody

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ABCB5 Mouse Monoclonal Antibody

Catalog #：EAB11923

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11923-30UL	In Stock	30ul	$133.50
EAB11923-100UL	In Stock	100ul	$298.50
EAB11923-200UL	In Stock	200ul	$508.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	90
Conjugate	Unconjugate
Specificity	ABCB5 Mouse Monoclonal Antibody detects endogenous levels of ABCB5 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	ATP binding cassette subfamily B member 5; ABCB5beta; EST422562; ABCB5alpha; ABCB5
Gene Aliases	ABCB5
UniProt ID	Q2M3G0
Entrez Gene ID	340273

Product Description

ABCB5(ATP-binding cassette sub-family B member 5) is a critical multi-pass membrane protein composed of 812 amino acids, belonging to the superfamily of ATP-binding cassette transporters. ABCB5 plays a significant role in the cellular transport of various molecules, utilizing energy derived from ATP hydrolysis to facilitate movement of substances across cellular membranes. Notably, ABCB5 is implicated in the development of chemoresistance in malignant melanomas, particularly in conferring resistance to the chemotherapeutic agent doxorubicin. The presence of two isoforms, alpha and beta, resulting from alternative splicing, adds complexity to function and regulation.

Product Image Gallery
Western blot analysis of extracts on Hela, 293T cells, using ABCB5 Mouse Monoclonal Antibody (EAB11923) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human breast caricnoma tissue, using ABCB5 Mouse Monoclonal Antibody (EAB11923) at 1:500 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol